- Siege (2010)
- Siege: Captain America (2010)
- Siege: Embedded (2010)
- Siege: Loki (2010)
- Siege: Secret Warriors (2010)
- Siege: Spider-Man (2010)
- Siege: The Cabal (2009)
- Siege: Young Avengers (2010)
- Sif (2010)
- Silent War (2007)
- Silly Tunes (1945-1947)
- Silver Sable, and the Wild Pack (1992-1995)
- Silver Surfer, Vol. 1 (1968-1970)
- Silver Surfer, Vol. 2 (1982)
- Silver Surfer, Vol. 3 (1987-1998)
- Silver Surfer, Vol. 4 (1988-1989, Epic)
- Silver Surfer, Vol. 5 (2003-2004)
- Silver Surfer, Vol. 6 (2011)
- Silver Surfer: Loftier Than Mortals (1999)
- Silver Surfer: Dangerous Artifacts (1996)
- Silver Surfer / Superman (1996)
- Silver Surfer/Warlock: Resurrection (1993)
- Silver Surfer/Weapon Zero (1997)
- Siren (1995, Malibu)
- Siren: Infinity (1995, Malibu)
- Sisterhood of Steel (1984, Epic)
- Six From Sirius, Vol. 1 (1984, Epic)
- Six From Sirius, Vol. 2 (1985, Epic)
- Six-Gun Western, Vol. 1 (1957, Atlas)
- Snafu (1955-1956, Atlas Comics)
- Spaceknights (2000)
- Spaceman (1953-1954, Atlas Comics)
- Space Squadron (1951-1952, Atlas Comics)
- Special Marvel Edition (1971)
- Special Edition X-Men (1983)
- Spectacular Scarlet Spider (1995)
- Spectacular Spider-Man Magazine (1968)
- Spectacular Spider-Man, Vol .1 (1976-1998)
- Spectacular Spider-Man, Vol .2 (2003-2005)
- Speedball (1988-1989)
- Spellbinders (2005)
- Spellbound (1952-1957, Atlas Comics)
- Spider-Girl (1998-2006)
- Spider-Man (1990-1998)
- Spider-Man Adventures (1994-1996)
- Spider-Man Family (2005)
- Spider-Man Family (2007-2008)
- Spider-Man: India (2004-2005)
- Spider-Man Noir (2009)
- Spider-Man Noir: Eyes Without A Face (2009-2010)
- Spider-Man - Limited Series (link to all limited series involving Spider-Man)
- Spider-Man - One-Shots (link to all "one-shot" Spider-Man titles)
- Spider-Man 2099 (1992-1996)
- Spider-Man Unlimited, Vol. 1 (1993-1998)
- Spider-Man Unlimited, Vol. 2 (1999-2000)
- Spider-Man Unlimited, Vol. 3 (2004-2006)
- Spider-Woman, Vol. 1 (1978-1983)
- Spider-Woman, Vol. 2 (1993-1994)
- Spider-Woman, Vol. 3 (1999-2000)
- Spider-Woman, Vol. 4 (2009-2010)
- Spider-Woman: Origin, Vol. 1 (2006)
- Spidey Super Stories (1974-1982)
- Spirits of Vengeance (1992-1994)
- Spitfire (2010)
- Spitfire and the Troubleshooters (1986-1987, New Universe)
- Spoof (1970-1973)
- Sports Action (1950-1952, Atlas Comics)
- Sports Stars (1949, Atlas Comics)
- Spyke (1993, Heavy Hitters)
- Spy Cases (1950-1953, Atlas Comics)
- Spy Fighters (1951-1953, Atlas Comics)
- Spy Thrillers (1954-1955, Atlas Comics)
- Stalkers (1990-1991, Epic)
- Star Brand (1986-1989, New Universe)
- Starblast (1994)
- Starjammers (All titles)
- Starlord (1996)
- Starlord Megazine (1996)
- Star-Lord Special Edition (1982)
- Star Masters (1995-1996)
- Starriors (1984-1985)
- Starstruck (1985, Epic)
- Startling Stories: The Thing (2003)
- Startling Stories: The Thing - Night Falls on Yancy Street (2003)
- Star Trek (1980)
- Star Wars (1977-1986)
- Star Wars: Return of the Jedi (1983-1984)
- Steelgrip Starkey (1986, Epic)
- Steeltown Rockers (1990)
- Steve Rogers: Super-Soldier (2010)
- St. George (1988-1989)
- Stories of Romance (1956-1957, Atlas Comics)
- Storm (All titles)
- Stormbreaker: The Saga of Beta Ray Bill
- Strange (2004-2005, Marvel Knights)
- Strange Combat Tales (1993-1994, Epic)
- Strange Stories of Suspense (1955-1957, Atlas Comics)
- Strange Tales (All titles)
- Strange Tales of the Unusual (1955-1957, Atlas Comics)
- Strange Worlds (1958-1959, Atlas Comics)
- Stray Toasters (1988)
- Street Poet Ray (1990)
- Strikeforce: Morituri (1986-1989)
- Strikeforce: Morituri Electric Undertow (1989)
- Strong Guy Reborn (1997)
- Stryfe's Strike File (1993)
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